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8 Reasons Why Clobetasol Propionate for Acne Is a Bad Idea

Acne is a persistent skin condition affecting many individuals across various ages. While there are numerous treatment options available, the use of clobetasol propionate for acne has gained attention, albeit for the wrong reasons. 

Clobetasol propionate is a potent topical corticosteroid typically used to treat skin issues like psoriasis or eczema. Applying this medicine to acne may lead to several adverse effects. In this article, we will delve into 8 reasons why clobetasol propionate for acne is a bad idea.

Also read: How to choose the best acne treatment

Biggest Take-Aways:

  • While effective for some skin conditions, Clobetasol propionate is unsuitable for acne treatment due to various risks and side effects.
  • Understanding how often you use a product and selecting treatments that align with specific skin needs is crucial for effectiveness.
  • Proper dosage, regularity, and adherence to instructions are vital for achieving desired outcomes in skin care.
  • Exposed Skin Care offers a specialized and safer alternative to clobetasol for acne treatment, focusing on individual needs and overall skin health without adverse effects.

Clobetasol propionate ointment on woman's fingertips

Reason 1: Potent Topical Steroid with Serious Side Effects

Clobetasol propionate is a potent topical steroid with severe consequences if misused. Using clobetasol propionate for acne could lead to the following issues:

Skin Atrophy and Stretch Marks

  • Thinning of Skin: Prolonged use of clobetasol on the face can cause the skin to thin and weaken.
  • Stretch Marks: The steroid can lead to stretch marks that might be permanent.

Adverse Reactions

  • Redness and Irritation: Constant application may cause skin redness and irritation.
  • Allergic Reaction: It may cause an allergic reaction, leading to itchiness and inflammation.

Reason 2: Inappropriate for Acne Treatment

Clobetasol is primarily used to treat inflammatory skin conditions, not acne vulgaris. Here's why it's unsuitable:

May Aggravate Acne

  • Inducing Perioral Dermatitis: This ointment may cause a pimple-like rash around the mouth.
  • Worsening Acne Vulgaris: It may exacerbate the existing acne condition.

No Efficacy in Controlled Trials

  • Lack of Evidence: No controlled trials support clobetasol's effectiveness in treating acne.

Woman applying Clobetasol propionate on acne

Reason 3: Risk of Adrenal Suppression

Clobetasol is a corticosteroid that may affect the adrenal glands. Here's how:

Adrenal Insufficiency

  • Suppressing Adrenal Function: Prolonged use of clobetasol propionate can lead to adrenal suppression.
  • Health Complications: This may result in various health complications related to the adrenal gland.

Reason 4: Not Meant for Long-Term Use

Clobetasol is usually prescribed for short-term treatment. Using it for acne may lead to:

Resistance and Dependency

  • Building Resistance: The skin may become resistant to the steroid's effects, requiring higher dosage.
  • Dependency Issues: Long-term use might lead to dependency, making it difficult to stop using the medicine.

Reason 5: Potential Impact on Rosacea

Clobetasol can also affect other skin conditions, such as rosacea. Here's how:

Worsening Rosacea

  • Increasing Redness: Clobetasol on your face may increase redness and inflame rosacea.
  • Potential Flare-ups: It may cause rosacea to flare up and become more severe.

Face redness or rash

Reason 6: Risk of Glaucoma and Other Eye Issues

Clobetasol propionate may cause eye-related problems. Here's why:

Increased Risk of Glaucoma

  • Raised Eye Pressure: Using clobetasol topical near the eyes might increase the risk of glaucoma.
  • Potential Vision Loss: Glaucoma can lead to vision loss if left untreated.

Reason 7: Possibility of Overdose and Poisoning

Misuse of clobetasol propionate could lead to severe consequences, such as overdose. Here's what can happen:

Symptoms of Overdose

  • Dizziness and Dryness: Overdosing on this ointment may cause dizziness and skin dryness.
  • Call 911: Call the local poison control center immediately in case of an overdose.

Woman having dizziness

Reason 8: Concerns About Off-Label Usage

Using clobetasol for acne is considered off-label usage. This brings up the following concerns:

Lack of Medical Guidance

  • No Specific Dosage Guidelines: There are no specific guidelines for using clobetasol to treat acne.
  • Potential Legal and Ethical Issues: Off-label usage without proper medical advice may lead to legal and ethical dilemmas.

An Alternative to Clobetasol: Benefits of Exposed Skin Care for Managing Acne

While clobetasol works for various skin conditions and is often used to treat inflammatory issues, it's unsuitable for acne treatment. On the other hand, Exposed Skin Care offers a comprehensive solution specially designed to manage acne without the risks associated with clobetasol. 
Exposed Skin Care Ultimate Kit

Here's how Exposed Skin Care stands out:

  • Quick Relief from Itching and Itchy Lesions: Offers relief within 4 weeks, reducing the itchy sensation often associated with acne lesions.
  • Avoids Possible Side Effects of Steroids: Unlike corticosteroids, Exposed Skin Care doesn't lead to side effects like thinning skin or occlusive issues.
  • Holistic Approach: Addresses various skin problems such as acne, skin infections, and inflammation without needing a bandage or injection that may change the skin's appearance.
  • Precaution for Sensitive Skin: Designed with care, considering the patient's medical information and medical history, to minimize the risk of drug interactions and other complications.
  • Reduces Risk: Unlike corticosteroids, which may increase your risk of systemic absorption into the bloodstream, Exposed Skin Care offers surface-level treatment.
  • Avoids Harsh Chemicals: No need for potent chemicals like hydrocortisone, which can cause crust or other skin issues.
  • Customized Care: Offers medication for acne based on individual needs, promoting long-term skin health.

By focusing on the root causes of acne and using natural extracts combined with advanced scientific ingredients, Exposed Skin Care provides a viable and safe alternative to clobetasol propionate for acne treatment. 


In the complex world of skincare, selecting the right products and understanding how often you use them can make a significant difference in the effectiveness of treatment. While clobetasol propionate is often employed for various skin conditions, it's clear that its usage for acne is fraught with challenges and risks.

On the other hand, Exposed Skin Care provides a more specialized approach to acne treatment without the adverse effects of clobetasol. It’s designed to meet the individual needs of users and supports overall skin health.

Yet, the focus should always remain on understanding the specific needs of your skin condition and selecting products that align with those needs. There's no one-size-fits-all solution, and a comprehensive understanding of various treatments and possible side effects is essential.

It's not just about what you use but how often you use it. Proper dosage, regularity, and adherence to instructions are crucial in achieving desired outcomes, whether soothing an itchy lesion or treating a more severe skin infection.

While clobetasol propionate has its place in treating some skin conditions, its application for acne appears inappropriate. The intricate balance of treatment and a considerate approach like that provided by Exposed Skin Care promotes a more nuanced, effective, and safe path to healthier skin.


Q: Can I use clobetasol on my face for acne treatment?

A: It is highly discouraged to use clobetasol on your face for acne as it may lead to various side effects, such as redness, irritation, and potential long-term harm.

Q: How long can I use clobetasol without risk of side effects?

A: Generally, clobetasol should not be used longer than 2 weeks in a row without medical supervision, as it can cause serious side effects.

Q: Is it safe to combine clobetasol with other acne medications?

A: Combining clobetasol with other acne medications may increase the risk of adverse effects. Always consult your doctor before using this combination therapy.

Q: What should I do if I miss a dose or need to wash my hands after applying clobetasol?

A: If you miss a dose, apply it as soon as you remember, but don't double up. Always wash your hands after applying unless you are treating an area of skin on the hands.

Q: Can clobetasol pass into breast milk or cause allergic reactions in the groin area?

A: Yes, clobetasol may pass into breast milk and cause allergic reactions in sensitive areas such as the groin. It's essential to consult your doctor before using this drug in these circumstances.