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What the Science Says About Supplements for Acne

Can oral supplements work as a treatment for acne? The true answer is complex.

With a complete skincare kit designed by experts, supplements such as probiotics can be valuable to your skincare routine. With that being said, supplements won't get rid of your acne on their own, and before you consider medication, you should first try a consistent skincare routine, which can treat your acne far more effectively and safely.

With a gentle skincare routine, you can significantly reduce the appearance of acne. And if you decide to add clear skin supplements to your skincare routine, first ensure that your chosen supplement uses high-quality ingredients that will help your skin without side effects.

Pills sit on a table.

What Are Supplements?

Supplements are products containing micronutrients and natural compounds (vitamins, minerals, plant extracts, and herbs) to supplement your diet. They are typically sold in pill form, but powder and liquid forms are also popular.

Because supplements are ingested orally, they are classified as a systemic treatment because they affect multiple body systems, unlike topical treatments, which are applied directly to the skin.

Supplements are often designed to make up for a specific deficiency in your diet, but research shows supplements cannot replace a healthy diet and lifestyle.

It is also worth noting that incorrectly using supplements can have unhealthy and even life-threatening side effects, which is why you should only get your clear skin supplements from a trusted source.

Supplements that Can Help Acne

Supplements like zinc, probiotics, and vitamin A might be practical additions to your skincare regimen. However, please note that these ingredients will not get rid of acne on their own and must be matched with a consistent morning and evening skincare routine.


Generally, supplementing your diet with balanced nutrients can target acne and improve skin health. Ingredients like zinc enhance immune system functioning, targeting multiple causes of acne. It does this by fighting off acne-causing bacteria, called p. acnes, and calming inflammation.

Taking too much zinc as a supplement can cause gastrointestinal distress and even lowered immunity. That's why we only include 15mg of zinc in our probiotic complex, which is enough to fulfill your daily needs without going overboard.

By Alchemist-hp


There is growing evidence of an extraordinary relationship between the gut and the rest of the body. The intestines host all kinds of bacteria, both good and bad. Supporting the good gut bacteria with a probiotic product may positively affect the skin.

Good probiotics include:

At Exposed, we've created our Probiotic Complex to help decrease inflammation on a systemic level to reduce acne on a skin level. We've added several essential vitamins like vitamin A and vitamin E and important nutrients like zinc and copper. Synergistically, they take advantage of most of the acne-fighting potential of natural supplements.

Vitamin A

Vitamin A for acne has been extensively studied in the realm of skincare.

Vitamin A has anti-inflammatory properties due to its high antioxidant contentAntioxidants fight free radicals and reduce cell destruction, boosting the immune system and leading to higher cell turnover and healthier skin. This immune system boost will help fight off P. acnes bacteria and regulate the life cycle of skin cells and the skin's oil production.

We should also note that excessive amounts of Vitamin A, typically coming from supplements, can be very harmful. So in our natural probiotic supplement for acne, we include 100% of your daily Vitamin A, no more, no less. That ensures that with one pill a day, you can consume the proper amount of Vitamin A without unintentionally taking too much.

A close-up photo of leaves.
Leafy greens are high in Vitamin A.

Supplements That Don't Help Acne

Fish Oil

You may have seen fish oil recommended for its Omega-3 fatty acids. These healthy fats are great for your body and help reduce inflammation, a leading cause of acne.

However, the study linked above showed very little change in the acne of its participants, and it is one of the very few studies performed on the effects of fish oil on acne. Due to limited research on this supplement, we recommend trying out the ingredients listed above and an effective skincare routine to get rid of your acne.


Some say that chasteberry, or vitex, may be an effective supplement, especially for hormonal acne in women. However, while it may increase progesterone, it may also increase estrogen and sustain the hormonal imbalance.

Dangers of Supplements

Like any medication, it is possible to take too many supplements, causing adverse effects. While toxicity due to overdosing is rare and potentially difficult to achieve, it is still a concern when taking any oral supplement.

In addition, due to limited regulation, you may not be able to trust every product you see. Because the US Food and Drug Administration (FDA) regulates these products like food products rather than medical products, you don't always know the quality of what you're ingesting. For example, makers of supplements are not required to indicate how effective the active ingredient truly is. For this reason, be sure to only use trusted brands for acne, such as Exposed Skincare.

Supplementing is Not Ideal On Its Own

In addition to supplementing, it is essential to have a well-rounded, topical skincare routine. Using products that target acne at the source, the skin, with both natural and scientific ingredients, will help to cure your blemishes.

At Exposed Skincare, we guarantee results. So if you don't get the results you're looking for in 30 days, you can get your money back, no questions asked.


A before and after image of the results of Exposed Skincare.
Victoria M cleared up her acne using Exposed Skincare kits.

Combining Skincare and Supplements to Treat Acne

Some supplements have significant, researched effects on acne, like Zinc, Probiotics, and Vitamin A, so we implement them in our Probiotic Complex. When combined with our cleanser, tonic, and morning and evening serums provided in our Basic Kit, you can attack acne from all angles, inside and out.