10 Best Acne Treatments on Amazon

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Acne is undoubtedly the most common skin condition, and due to an overwhelming majority of the affected populations, countless acne treatments have come into existence, and all can be found on Amazon. However, not all of these treatments have been created on the same level. It is crucial to the betterment of your skin that you find a clear skin treatment plan that consists of natural acne-fighting ingredients. Below are the Best Reviewed Acne Treatment Kits and Products on Amazon

The first step toward treating your acne is understanding it; diagnosis is the first stage of treatment. The next step is choosing the right type of acne treatment according to your specific needs and requirements.

Best Acne Treatments on Amazon

1) Exposed Skin Care

4.5 stars over the past 12 months

The number one spot goes to Exposed Skin Care. The best aspect of the Exposed Skin Care Acne Treatment Kits are the delivery of fast results, and the exclusive amalgamation of Science and Nature that synergizes their individual functions to provide a much clearer and smoother skin. Exposed Skin Care products use a unique blend of acne-fighting actives combined with natural botanicals and extracts that sooth and regenerate the skin. It’s an innovative approach that’s been proven effective.

It is evident that Exposed prioritizes quality over anything else. While proven to be very safe to use as these products do not overpower your skin like the majority of other products do, it uses a calming blend of natural ingredients to heal and soothe the skin, all the while clearing up your acne.

They called on a team of dermatologists, cosmetologists, naturopaths, and chemists to use their scientific knowledge and clinical experience to develop the first full spectrum system that treats and prevents acne in ways that were previously thought impossible.

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This five-piece kit of essential daily treatments quickly gets acne under control. The products are designed to work together to clean skin, treat and prevent blemishes, and restore radiance. It’s an easy-to-use system proven to give you clear, beautiful skin in 30 days or less.

  • Facial Cleanser 4 fl. oz.
  • Clearing Tonic 4 fl. oz.
  • Acne Treatment Serum 1.7 fl. oz.
  • Clear Pore Serum 1.7 fl. oz.
  • Free Derm-X Cloth


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This six-piece system treats acne-prone skin and boosts hydration without clogging pores. The products are designed to work together to clean skin, treat and prevent blemishes, and restore moisture and balance. The most popular kit, it’s easy-to-use and proven to give you clear, radiant skin in 30 days or less.

  • Facial Cleanser 4 fl. oz.
  • Clearing Tonic 4 fl. oz.
  • Acne Treatment Serum 1.7 fl. oz.
  • Clear Pore Serum 1.7 fl. oz.
  • Moisture Complex 1.7 fl. oz.
  • Free Derm-X Cloth


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This nine-piece kit has everything skin needs for ongoing clarity and balance. The products are designed to work together to clean skin, treat and prevent blemishes, and improve tone and texture. It goes beyond the essentials, with complexion boosting solutions that support clear skin, from the inside out.

  • Facial Cleanser 4 fl. oz.
  • Clearing Tonic 4 fl. oz.
  • Acne Treatment Serum 1.7 fl. oz.
  • Clear Pore Serum 1.7 fl. oz.
  • Moisture Complex 1.7 fl. oz.
  • Microderm Scrub 1.7 fl. oz.
  • Clarifying Mask 1.7 fl. oz.
  • Probiotic Complex 60 capsules
  • Free Derm-X Cloth


10) Clean and Clear acne treratment on Amazon

Clean & Clear’s 3-step Advantage Acne Control kit comes with the Acne Control Cleanser, the Fast-Acting Treatment, and the Hydrating Gel Moisturizer. This treatment is intended to fight against breakouts without over-drying the skin. Moreover, it treats existing pimples while helping prevent new ones from forming. It not only treats and prevents acne, but also blackheads and oily skin.  

9) Proactiv acne treatment on Amazon

The Proactiv Acne Treatment System enables your skin to effectively treat and prevent acne breakouts with clinically-proven acne-combating ingredients. The kit comes with a cleanser, toner, and a repairing solution.

Both the renewing cleanser and the repairing lotion contain benzoyl peroxide which is a well-known acne medication. It is known to kill and prevent all acne bacteria.

The alcohol-free toner helps you remove excess oil and unstiffen the skin using glycolic acid. This kit also features a Proactiv refining mask formulated with acne-combating sulfur. It helps eliminate impurities and diminish the occurrence of pores.

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Better ingredients equals clear skin vs any other brand

8) Clinique acne treatment on Amazon

Clinique’s Acne Solutions Clear Skin System kit contains 4 weeks’ worth of supply. It offers a gentle and non-irritating solution to acne. It is highly effective, and it is guaranteed that you will quickly notice fewer blemishes, smaller-looking pores, and less oily or red skin. This is a 3-step acne treatment system; cleanse, exfoliate, and moisturize.

The Acne Solutions Cleansing Foam, to cleanse your face with, along with the Clarifying Lotion, contains Salicylic Acid which is predominantly suited to curing a milder form of acne. It helps to unclog pores and prevent lesions.

7) Murad acne treatment on Amazon

Murad’s Acne Control Kit provides a complete, round the clock regimen for effectively eliminating breakouts. While doing so, it works to gently soothe irritation and restore healthy skin. The associated aim with the manufacture of Acne Complex is to provide a healthier, purer skin while effectively controlling oil and redness, and reducing acne.

The Acne Control Kit comes with a Clarifying Cleanser for preventing breakouts. Its Acne Clearing Solution is used to treat breakouts and soothe redness without having you end up with over-dried skin. Moreover, Oil-Control Mattifier SPF 15 instantly controls oil for over 8 hours.

6) AcneFree acne treatment on Amazon

AcneFree comes with 3 varying types of acne treatment kits:

  • “24H Acne Clearing System” for mild to moderate acne.
  • “Severe” for stubborn and severe acne.
  • “Sensitive Skin” for acne-prone skin that is typically irritable to drying acne solutions.

The most popular one is the 24H Acne Clearing System that has been clinically proven to deliver exceptional results. It coalesces acne-combating actives with caring ingredients for the rapid treatment of acne breakouts during which it effectively balances the skin.

The Oil-Free Purifying Acne Cleanser aims at treating and preventing blemishes and blackheads. Control shine with the Corrective Toner uses 10% witch hazel for restoring pH balance, glycolic acid for in-depth penetration, and Aloe Vera that effectively reduces inflammation. You can finish off with their Repair Lotion that is to be left overnight.

5) MD Complete acne treatment on Amazon

MD Complete’s Acne Clearing System Kit has proven to show dermatologist-level, skin clearing results. The treatment combines a high potency Retinoid, which is Pure Retinol, with Benzoyl Peroxide. Retinol works against wrinkles, uneven skin tone, and acne breakouts. Whereas the BPO, combined with the Retinol, works against the acne spots. Moreover, MD Complete has aimed to enhance this combination by further adding Vitamins B, C, as well as naturally-derived nutrients.

4) CleaRx acne treatment on Amazon

CleaRx’s Acne treatment kit is possibly one of the most effective over-the-counter treatments directed towards fighting moderate to severe acne. CleaRx is the very first “Maximum Strength Over-The-Counter Acne Regimen” designed for both adults and teens. CleaRx functions by killing the acne-causing bacteria, unclogging blocked pores, curing skin lesions, and normalizing your skin’s sebum production levels to reduce any redness and inflammation.

3) Neutralyze acne treatment on Amazon

Neutralyze’s Anti-Acne Solution has been clinically-proven to deliver ground-breaking results; you will start to see a noticeable improvement in only 2 to 3 days. The acne treatment kit includes the Neutralyze Face Wash, the Neutralyze Clearing, and the Neutralyze Synergyzer. Neutralyze is backed by Nitrogen Boost Skincare Technology. It offers the world’s very first acne solution that adds the power of Nitric Oxide, thereby promoting skin healing to enable instant acne treatment.

2) SMACNE acne treatment on Amazon                                         

SMACNE’s Acne Treatment Kit features 2 varying versions:

  • Original Formula Kit:

This treatment offers a non-irritating and deep-penetrating acne treatment suitable for sensitive to normal skin types.

  • Severe Acne Kit:

This deep-penetrating acne treatment is aimed to cure the stubborn and severe acne cases.

The kit contains a gentle Aloe Cleanser that uses Salicylic Acid. It is infused with Aloe Vera to act as an anti-inflammatory solution.  It also contains a Treatment solution that contains BPO, Salicylic Acid, and tea tree oil for acne.